Much of the development around bioabsorbable stents and other bioabsorbable implants have focused on a polymer, PLLA (poly-L-lactic acid) as the base material. Some new research indicates that a Zinc alloy may make a better bioabsorbable stent as compared to PLLA. The Zinc would degrade through a corrosion mechanism.
For more information, see:
QMED Online, Jan.16, 2014:
“…The most advanced absorbable stents available today are made from polylactic acid (PLLA). Based on nearly five years of clinical trial data, for example, Abbott Vascular’s bioresorbable Absorb scaffold compares favorably to the company’s metal-based XIENCE stent, the current industry standard for nonabsorbable drug-eluting stents….”
Also, see the link to research by Patrick Bowen, Jaroslaw Drelich, and others at Michigan Tech from April 30, 2013 with figures:
Patrick Bowen also indicates that a preprint of the paper accepted for publication in Journal of Advanced Materials, March 14, 2013, entitled: “Zinc Exhibits Ideal Physiological Corrosion Behavior for Bioabsorbable Stents” is available at:
Some highlights of the discussion include:
Even the Chairman of the Federal Reserve sometimes seriously understates reality:
From the IMPO Magazine at:
WASHINGTON (AP) — In his final public appearance as chairman of the Federal Reserve, Ben Bernanke took a moment to reflect on the 2008 financial crisis and compared it to a very bad car crash.
During an interview at the Brookings Institute, he recalls some “very intense periods” during the crisis, similar to trying to keep a car from going over a bridge after a collision. But after some time, he looked back and said, “Oh my God.”
Bernanke admits to some sleepless nights after Lehman Brothers collapsed in September 2008 and triggered the worst financial meltdown since the Great Depression.
Bernanke is stepping down as chairman at the end of the month. He will be replaced by Janet Yellen.
Smart phones and similar devices have very valuable patents and high-stakes patent litigation. There are also high stakes in medical devices. Read about this jury verdict below:
Jury Rules Medtronic Willfully Infringed TAVI Heart Valve Patent from Edwards Lifesciences
This story was published in Medical Product Oursourcing (MPO) at:
Medtronic Inc.’s CoreValve system infringes on a patent of Edwards Lifesciences Corp., according to the ruling of a federal court jury in Delaware on Jan. 15. The ruling, part of an ongoing legal battle between the two companies, holds Medtronic liable for $393.6 million in damages.
CoreValve is used in a transcatheter aortic valve implantation (TAVI) procedure, a minimally invasive treatment option for people with severe aortic stenosis. It received CE mark in Europe in 2007, but is not yet available in the United States. Minneapolis, Minn.-based Medtronic expects U.S. Food and Drug Administration approval by the completion of its 2014 fiscal year (end of April). Edwards has had the U.S. aortic valve market to itself since November 2011. Analysts expect TAVI to be a $3 billion worldwide market by the end of the decade.
Edwards and Medtronic are the two largest players in the European market for transcatheter aortic valves. And, perhaps as a result, the companies are no strangers to this sort of court battle. They have battled it out in U.S. and European courts before about patents held by Irvine, Calif.-based Edwards.
A colleague pointed me to this very interesting article in the Dec 31, 2013 Washington Post written by Brian Fung. The article highlights some of the significant differences between the duration of copyright protection versus patent protection. And also points out a number of iconic works that would be in the public domain now except for Congressional extensions of copyright protection.
The title of the article is: “If not for Congress, Superman, Lassie and Scrabble would be free for anyone to reproduce tomorrow”.
After the copyright extensions by Congress in 1998, works before 1978 can have copyright protection for up to 95 years!!
The author points out that:
“On Jan. 1, a whole raft of artistic and intellectual works will be making their way into the public domain — or they would be if Congress hadn’t extended copyright terms for the umpteenth time in 1998. At its core, copyright is meant to protect authors and creators. But as we’ve seen recently with a battle over Sherlock Holmes, copyrights can sometimes prevent well-meaning fans from showing the depth of their appreciation for a work by becoming creators themselves.”
“These days things that were published before 1978 enjoy copyright protections of up to 95 years, but that wasn’t always the case. Under the rules Congress made before the most recent term extension, rights-holders of older works were protected for just 75 years — at which point the work would enter the public domain and be free for anyone to use or riff upon.”
See the full article for more details:
Today I posted the movie that was shot live from Black Mountain of the 1988 explosion at the PEPCON Plant in Henderson, NV. This is one of the most incredible movies of an accident that you will ever see because it captured almost the entire sequence of a process plant fire and several explosions; an incredible disaster while it was in progress. Go to the Articles menu and read the background and details on this accident. Then hit the link “Click for Movie of actual Explosion“. You will be amazed!! It is rare for an accident of this speed and magnitude to be filmed as events unfold!! (Note: You can also use the highlighted links from this Blog post). Dr. Kim Parnell worked extensively on this investigation while at Exponent.
The new parnell-eng.com website is now live. Please visit and see the updated content.